Sildenafil was unfavorable in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity.Thus, the metabolite is answerable for about 20% of sildenafil's motion. Sildenafil is excreted as metabolites predominantly in the feces (about … Read More